Syk Inhibitor II - CAS 227449-73-2 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 574712
• Cas Number: 227449-73-2
• Formula: C₁₄H₁₅F₃N₆O•2HCl•2H₂O
• Purity: ≥95% by HPLC
• Description: A cell-permeable pyrimidine-carboxamide compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Syk (IC 50 = 41 nM), while affecting PKC ε , PKC βII , ZAP-70, Btk, and Itk only at much higher concentrations (IC 50 = 5.1, 11, 11.2, 15.5, and 22.6 µM, respectively)

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