MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem

Name MARK/Par-1 Activity Inhibitor, 39621 - Calbiochem
Supplier EMD Millipore
Catalog 454870
Formula C₂₁H₂₁N₃O₃S
Purity ≥98% by HPLC
Description A cell-permeable dihydropyrazinyl-thioacetamide that acts as an ATP-competitive MARK inhibitor (IC 50 = 3.6 µM; [ATP] = 100 µM) with much reduced or little activity against GSK-3β, SAD-kinase B/BRSK-1, MARKK/TAO-1, Cdc2/cycB, and p38/SAPK (30%, 20%, 11%, 4%, and 0% inhibition, respectively; [inhibitor] = 50 µM)
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