Lck Inhibitor - CAS 213743-31-8 - Calbiochem
| Name | Lck Inhibitor - CAS 213743-31-8 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 428205 |
| Cas Number | 213743-31-8 |
| Formula | C₂₃H₂₂N₄O |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable pyrrolopyrimidine compound that acts as a potent, reversible, selective, and ATP-competitive inhibitor of Lck (IC 50 at 5 µM ATP = < 1 nM, 2 nM, 70 nM, 1.57 µM and 1.98 µM for lck 64-509 Y 394 , Lckcd pY 394 , Src, Kdr and Tie-2, respectively; IC 50 at 1 mM ATP = 16 µM, 66 nM, 126 nM, 420 nM and 5.18 µM for Lck 64-509 Y 394 , Blk, Fyn, Lyn and Csk, respectively) |
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