HDAC Inhibitor XXIII, Tubastatin A - Calbiochem
| Name | HDAC Inhibitor XXIII, Tubastatin A - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 382187 |
| Formula | C₂₀H₂₁N₃O₂ |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable carbazolohydroxamate whose zinc-chelating hydroxamic acid moiety and catalytic channel rim-targeting aromatic cap structure render it a highly potent HDAC6-selective inhibitor (IC 50 = 15 nM against recombinant human HDAC6) with much reduced or no activity against HDAC8, HDAC1 (IC 50 = 0.854 and 16.4 µM, respectively), and other known HDACs (HDAC2/3/4/5/7/9/10/11; IC 50 >30 µM) |
| Supplier Page | Shop |
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