Name | γ-Secretase Inhibitor XXIII, Aβ42-Selective - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 565792 |
Formula | C₃₀H₃₉N₇O |
Purity | ≥95% by HPLC |
Description | A cell-permeable purine compound that acts as a highly potent and selective inhibitor against γ-secretase-mediated production of Aβ42 over Aβ40 (IC 50 = 21 and 350 nM, respectively) and Notch1 (Notch IC 50 / Aβ42 IC 50 >2400) in cultures in vitro |
Supplier Page | Shop |