γ-Secretase Inhibitor XXIII, Aβ42-Selective - Calbiochem

Name γ-Secretase Inhibitor XXIII, Aβ42-Selective - Calbiochem
Supplier EMD Millipore
Catalog 565792
Formula C₃₀H₃₉N₇O
Purity ≥95% by HPLC
Description A cell-permeable purine compound that acts as a highly potent and selective inhibitor against γ-secretase-mediated production of Aβ42 over Aβ40 (IC 50 = 21 and 350 nM, respectively) and Notch1 (Notch IC 50 / Aβ42 IC 50 >2400) in cultures in vitro
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