Name | IKK-2 Inhibitor XI - CAS 354810-80-3 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 401490 |
Cas Number | 354810-80-3 |
Formula | C₁₂H₁₁N₃O₂S |
Purity | ≥97% by HPLC |
Description | A cell-permeable thiophenecarboxamide-ureido compound that acts as a potent, ATP-binding pocket-targeting inhibitor of IKK-2 (IC 50 = 25 nM), while affecting IKK-1 and JNK1 only at much higher concentrations (IC 50 = 1.0 and 1.6 µM, respectively) |
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