IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem
| Name | IKK Inhibitor XII - CAS 928655-63-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 401491 |
| Cas Number | 928655-63-4 |
| Formula | C₁₉H₁₆ClN₃O₃S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable amino-diarylbenzamide compound that acts as a potent ATP site-targeting inhibitor against IKK-1 and IKK-2 (pIC 50 = 6.4 and 7.0, respectively), while exhibiting more than 50-fold less potency toward a panel of greater than 50 other kinases, including IKK-3 (pIC 50 <4.8), ALK5, Cdk-2, EGFR, ErbB2, GSK-3β, Plk1, Src, and VEGFR-2 |
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