PI 3-Kα Inhibitor IV - CAS 1188890-32-5 - Calbiochem
| Name | PI 3-Kα Inhibitor IV - CAS 1188890-32-5 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 528111 |
| Cas Number | 1188890-32-5 |
| Formula | C₁₆H₁₅N₃O₂S•2HCl |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable morpholino-thienopyrimidine compound that acts as a potent and isoform-selective inhibitor of PI 3-Ks (IC 50 = 2 nM, 16 nM, 660 nM, and 220 nM for p110α, p110β p110γ, and PI 3-K C2β, respectively) and inhibits non-PI 3-K kinases only at much higher concentrations (IC 50 ≥ 3.4 µM for Cdk2/E, KDR, PKA, and PKCα) |
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