Anaphase-Promoting Complex Inhibitor, TAME - CAS 1784-03-8 - Calbiochem

Name Anaphase-Promoting Complex Inhibitor, TAME - CAS 1784-03-8 - Calbiochem
Supplier EMD Millipore
Catalog 172104
Cas Number 1784-03-8
Formula C₁₄H₂₂N₄O₄S·HCl
Purity ≥98% by HPLC
Description TAME is a potent ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation by directly binding to APC and disrupts the IR-tail-dependent interactions between APC and its activator proteins Cdc20 or Cdh1
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