Glutaminase Inhibitor, Compound 968 - Calbiochem

Name Glutaminase Inhibitor, Compound 968 - Calbiochem
Supplier EMD Millipore
Catalog 352010
Formula C₂₇H₂₇BrN₂O
Purity ≥99% by HPLC
Description A cell-permeable benzophenanthridinone compound that acts as an allosteric and reversible inhibitor of mitochondrial glutaminase activity and represses the growth and invasive activity in glutaminase upregulated fibroblasts and in tumor cells (IC 50 ≤ 10 µM in NIH3T3 cells stably expressing Dbl, Cdc42-F28L, Rac-F28L or RhoC-F30L mutants and in SKBR3 and MDA-MB231 cancer cells)
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