PKR Inhibitor - CAS 608512-97-6 - Calbiochem
| Name | PKR Inhibitor - CAS 608512-97-6 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 527450 |
| Cas Number | 608512-97-6 |
| Formula | C₁₃H₈N₄OS |
| Purity | ≥90% by HPLC |
| Description | An imidazolo-oxindole compound that acts as a potent, ATP-binding site directed inhibitor of PKR. Shown to effectively inhibit RNA-induced PKR autophosphorylation (IC 50 = 210 nM) and rescue PKR-dependent translation block (IC 50 = 100 nM) |
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