CEP-701 - CAS 111358-88-4 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 219499
• Cas Number: 111358-88-4
• Formula: C₂₆H₂₁N₃O₄•0.5H₂O•0.5C₃H₈O
• Purity: ≥98% by HPLC
• Description: A cell-permeable indolocarbazole that is reported to inhibit the activity of several tyrosine kinases, including JAK2/3, Flt3, TrkA, Flk1/KDR/VEGFR2, (IC 50 = 0.9, 3, 3.4, and 65 nM, respectively, in cell-free kinase assays) and RET, while exhibiting much reduced potency against PKC and PDGFRβ (IC 50 = 218 and 773 nM, respectively) and little or no effect towards EGFR, βIRK, FMS, KIT, or Bcr-Abl

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