AICAR
| Name | AICAR |
|---|---|
| Supplier | Cell Signaling Technology |
| Catalog | 9944 |
| Prices | $99.00 |
| Sizes | 25 mg |
| Formula | C9H14N4O5 |
| Molecular Weight | 258.24 g/mol |
| Purity | >99% |
| Description | AICAR (5-Aminoimidazole-4-carboxyamide ribonucleoside) is an adenosine analog taken up by muscle and phosphorylated to form 5-aminoimidazole-4-carboxamide-1--D-ribofuranosyl-5'-monophosphate (ZMP), which stimulates AMPK activity and glucose transport in skeletal muscle (1). AICAR has been used in studies measuring glucose uptake, diabetes and insulin resistance, and energy regulation during exercise. AICAR acts by entering nucleoside pools and significantly increasing levels of adenosine during periods of ATP breakdown (2). |
| Supplier Page | Shop |
Product images
Western Blot analysis of extracts from C2C12 cells, cultured in the presence or absence of serum (O/N) and treated with or without AICAR (0.5 mM, 30 min), using Phospho-AMPKalpha (Thr172) (40H9) Rabbit mAb #2535.