Calyculin A
| Name | Calyculin A |
|---|---|
| Supplier | Cell Signaling Technology |
| Catalog | 9902 |
| Prices | $79.00 |
| Sizes | 10 µg |
| Formula | C50H81N4O15P |
| Purity | >98% |
| Description | Calyculin A inhibits the activity of protein phosphatases PP1 and PP2A (1,2). Unlike Okadaic acid, which reduces PP2A activity but has little effect on PP1 activity, Calyculin A inhibits both phosphatases (1). Neither Calyculin A nor Okadaic acid inhibit acid or alkaline phosphatases or phospho- tyrosine protein phosphatases (2). |
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Product images
Western blot analysis of extracts from Jurkat cells, untreated or treated with Calyculin (0.1 µM for 45 minutes prior to lysis), using P-Thr-Polyclonal #9381. Proteins were separated by 2D electrophoresis prior to blotting.
Western blot analysis of extracts from A431 cells treated with varied concentrations of Okadaic Acid or Calyculin A (30 minutes) using P-Thr-Polyclonal #9381.