Dasatinib
| Name | Dasatinib |
|---|---|
| Supplier | Cell Signaling Technology |
| Catalog | 9052 |
| Prices | $59.00 |
| Sizes | 5 mg |
| Formula | C22H26ClN7O2S |
| Molecular Weight | 488.01 g/mol |
| Purity | >99% |
| Description | Dasatinib is a small molecule inhibitor of both the Src and Bcr-Abl tyrosine kinases, with IC 50 values of 0.55 and 3.0 nM for the isolated kinases, respectively (1). Imatinib and dasatinib have similar inhibitory mechanisms, but dasatinib displays greater potency in imatinib-resistant cell lines and greater inhibitory effect on platelet derived growth factor (PDGF) (2,3). |
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