Trichostatin A (TSA)
| Name | Trichostatin A (TSA) |
|---|---|
| Supplier | Cell Signaling Technology |
| Catalog | 9950 |
| Prices | $109.00 |
| Sizes | 1 mg |
| Formula | C17H22N2O3 |
| Molecular Weight | 302.4 g/mol |
| Purity | >99% |
| Description | Trichostatin A is an antifungal antibiotic derived from Streptomyces that inhibits mammalian histone deacetylases (1,2). When used at nanomolar concentrations, trichostatin A causes the accumulation of acetylated histones in a quite specific and reversible manner (2,3). Trichostatin A has also been shown to inhibit both G1- and G2-phases of the mammalian cell cycle and has been tested for use as a potential anticancer agent (2-5). |
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Product images
Western blot analysis of extracts from various cell lines, untreated or TSA-treated (400 nM for 12 hours), using Acetyl-Histone H2A (Lys5) Antibody.