Ro 25-6981 maleate

• Supplier: R&D Systems
• Catalog: 1594
• Prices: $79.00, $169.00, $705.00
• Sizes: 1 mg, 10 mg, 50 mg
• Cas Number: 1312991-76-6
• Chemical Name: (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanolmaleate
• Formula: C22H29NO2.C4H4O4
• Molecular Weight: 455.55
• Purity: >98%

Product References

Multiple roles of GluN2B-containing NMDA receptors in synaptic plasticity in - Multiple roles of GluN2B-containing NMDA receptors in synaptic plasticity in

France G, Fernandez-Fernandez D, Burnell ES, Irvine MW, Monaghan DT, Jane DE, Bortolotto ZA, Collingridge GL, Volianskis A. Neuropharmacology. 2017 Jan;112(Pt A):76-83. doi:

beta-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and - beta-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and

Chen G, Xie RG, Gao YJ, Xu ZZ, Zhao LX, Bang S, Berta T, Park CK, Lay M, Chen W, Ji RR. Nat Commun. 2016 Aug 19;7:12531.

MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA - MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA

Volkmann RA, Fanger CM, Anderson DR, Sirivolu VR, Paschetto K, Gordon E, Virginio C, Gleyzes M, Buisson B, Steidl E, Mierau SB, Fagiolini M, Menniti FS. PLoS One. 2016 Feb 1;11(2):e0148129.

Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA - Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA

Lauderdale K, Murphy T, Tung T, Davila D, Binder DK, Fiacco TA. ASN Neuro. 2015 Oct 21;7(5). pii: 1759091415605115. doi:

ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by - ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by

Tindi JO, Chavez AE, Cvejic S, Calvo-Ochoa E, Castillo PE, Jordan BA. J Neurosci. 2015 Jun 17;35(24):8986-96.

A role for picomolar concentrations of pregnenolone sulfate in synaptic - A role for picomolar concentrations of pregnenolone sulfate in synaptic

Smith CC, Martin SC, Sugunan K, Russek SJ, Gibbs TT, Farb DH. Mol Pharmacol. 2014 Oct;86(4):390-8.

Knockdown of BNST GluN2B-containing NMDA receptors mimics the actions of ketamine - Knockdown of BNST GluN2B-containing NMDA receptors mimics the actions of ketamine

Louderback KM, Wills TA, Muglia LJ, Winder DG. Transl Psychiatry. 2013 Dec 3;3:e331.

Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors - Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors

Trepanier C, Lei G, Xie YF, MacDonald JF. Sci Rep. 2013;3:926.

Protein tyrosine phosphatase alpha in the dorsomedial striatum promotes excessive - Protein tyrosine phosphatase alpha in the dorsomedial striatum promotes excessive

Ben Hamida S, Darcq E, Wang J, Wu S, Phamluong K, Kharazia V, Ron D. J Neurosci. 2013 Sep 4;33(36):14369-78.

Treatment with a clinically-relevant dose of methylphenidate alters NMDA receptor - Treatment with a clinically-relevant dose of methylphenidate alters NMDA receptor

Urban KR, Li YC, Gao WJ. Neurobiol Learn Mem. 2013 Mar;101:65-74.