A 769662

• Supplier: R&D Systems
• Catalog: 3336
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Cas Number: 844499-71-4
• Chemical Name: 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
• Formula: C20H12N2O3S
• Molecular Weight: 360.39
• Purity: >98%

Product References

AMP-activated protein kinase (AMPK) activator A-769662 increases intracellular - AMP-activated protein kinase (AMPK) activator A-769662 increases intracellular

Vlachaki Walker JM, Robb JL, Cruz AM, Malhi A, Weightman Potter PG, Ashford MLJ, McCrimmon RJ, Ellacott KLJ, Beall C. Diabetes Obes Metab. 2017 Jul;19(7):997-1005.

mTOR controls lysosome tubulation and antigen presentation in macrophages and - mTOR controls lysosome tubulation and antigen presentation in macrophages and

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Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in - Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in

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Intact LKB1 activity is required for survival of dormant ovarian cancer - Intact LKB1 activity is required for survival of dormant ovarian cancer

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Enhanced Production of Adenosine Triphosphate by Pharmacological Activation of - Enhanced Production of Adenosine Triphosphate by Pharmacological Activation of

Hwang JH, Kim YH, Noh JR, Choi DH, Kim KS, Lee CH. Mol Cells. 2015 Oct;38(10):843-50.

Dynamics of elongation factor 2 kinase regulation in cortical neurons in response - Dynamics of elongation factor 2 kinase regulation in cortical neurons in response

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Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial - Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial

Weikel KA, Cacicedo JM, Ruderman NB, Ido Y. Am J Physiol Cell Physiol. 2015 Feb 1;308(3):C249-63. doi:

A novel MEK-ERK-AMPK signaling axis controls chemokine receptor CCR7-dependent - A novel MEK-ERK-AMPK signaling axis controls chemokine receptor CCR7-dependent

Lopez-Cotarelo P, Escribano-Diaz C, Gonzalez-Bethencourt IL, Gomez-Moreira C, Deguiz ML, Torres-Bacete J, Gomez-Cabanas L, Fernandez-Barrera J, Delgado-Martin C, Mellado M, Regueiro JR, Miranda-Carus ME, Rodriguez-Fernandez JL. J Biol Chem. 2015 Jan 9;290(2):827-40.

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo - Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo

Mo JS, Meng Z, Kim YC, Park HW, Hansen CG, Kim S, Lim DS, Guan KL. Nat Cell Biol. 2015 Apr;17(4):500-10.

Bidirectional regulation of P body formation mediated by eIF4F complex formation - Bidirectional regulation of P body formation mediated by eIF4F complex formation

Melemedjian OK, Mejia GL, Lepow TS, Zoph OK, Price TJ. Neurosci Lett. 2014 Mar 20;563:169-74.