SCH 79797 dihydrochloride

• Supplier: R&D Systems
• Catalog: 1592
• Prices: $225.00, $925.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1216720-69-2
• Chemical Name: N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diaminedihydrochloride
• Formula: C23H25N5.2HCl
• Molecular Weight: 444.41
• Purity: >99%

Product References

Interference with Protease-activated Receptor 1 Alleviates Neuronal Cell Death - Interference with Protease-activated Receptor 1 Alleviates Neuronal Cell Death

Li Y, Yang W, Quinones-Hinojosa A, Wang B, Xu S, Zhu W, Yu F, Yuan S, Lu P. Sci Rep. 2016 Dec 2;6:38247.

Thrombin-induced reactive oxygen species generation in platelets: A novel role - Thrombin-induced reactive oxygen species generation in platelets: A novel role

Carrim N, Arthur JF, Hamilton JR, Gardiner EE, Andrews RK, Moran N, Berndt MC, Metharom P. Redox Biol. 2015 Dec;6:640-7.

PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone - PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone

Gur-Cohen S, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, Golan K, Kalinkovich A, Ledergor G, Wong E, Niemeyer E, Porat Z, Erez A, Sagi I, Esmon CT, Ruf W, Lapidot T. Nat Med. 2015 Nov;21(11):1307-17.

Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen - Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen

Tripathi T, Abdi M, Alizadeh H. Invest Ophthalmol Vis Sci. 2014 May 29;55(6):3912-21.

Thrombin conducts epithelialmesenchymal transition via proteaseactivated - Thrombin conducts epithelialmesenchymal transition via proteaseactivated

Otsuki T, Fujimoto D, Hirono Y, Goi T, Yamaguchi A. Int J Oncol. 2014 Dec;45(6):2287-94.

Induction of tumor necrosis factor (TNF) release from subtypes of T cells by - Induction of tumor necrosis factor (TNF) release from subtypes of T cells by

Yang H, Li T, Wei J, Zhang H, He S. Mediators Inflamm. 2013;2013:165453.

Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and - Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and

Juncker-Jensen A, Deryugina EI, Rimann I, Zajac E, Kupriyanova TA, Engelholm LH, Quigley JP. Cancer Res. 2013 Jul 15;73(14):4196-211.

Role of SCH79797 in maintaining vascular integrity in rat model of subarachnoid - Role of SCH79797 in maintaining vascular integrity in rat model of subarachnoid

Yan J, Manaenko A, Chen S, Klebe D, Ma Q, Caner B, Fujii M, Zhou C, Zhang JH. Stroke. 2013 May;44(5):1410-7.

Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration. - Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration.

Gadepalli R, Kotla S, Heckle MR, Verma SK, Singh NK, Rao GN. J Biol Chem. 2013 Oct 25;288(43):30815-31.

Kallikrein 6 is a novel molecular trigger of reactive astrogliosis. - Kallikrein 6 is a novel molecular trigger of reactive astrogliosis.

Scarisbrick IA, Radulovic M, Burda JE, Larson N, Blaber SI, Giannini C, Blaber M, Vandell AG. Biol Chem. 2012 Apr;393(5):355-67.