LRRK2-IN-1

Name LRRK2-IN-1
Supplier R&D Systems
Catalog 4273
Prices $255.00, $1,045.00
Sizes 10 mg, 50 mg
Cas Number 1234480-84-2
Chemical Name 5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
Formula C31H38N8O3
Molecular Weight 570.09
Purity >98%
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Product References

LRRK2 kinase activity and biology are not uniformly predicted by its - LRRK2 kinase activity and biology are not uniformly predicted by its

Reynolds A, Doggett EA, Riddle SM, Lebakken CS, Nichols RJ. Front Mol Neurosci. 2014 Jun 24;7:54.

The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: - The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells:

Saez-Atienzar S, Bonet-Ponce L, Blesa JR, Romero FJ, Murphy MP, Jordan J, Galindo MF. Cell Death Dis. 2014 Aug 14;5:e1368.

Phosphorylation of LRRK2 by casein kinase 1alpha regulates trans-Golgi clustering - Phosphorylation of LRRK2 by casein kinase 1alpha regulates trans-Golgi clustering

Chia R, Haddock S, Beilina A, Rudenko IN, Mamais A, Kaganovich A, Li Y, Kumaran R, Nalls MA, Cookson MR. Nat Commun. 2014 Dec 15;5:5827.