Pirenzepine dihydrochloride

Name Pirenzepine dihydrochloride
Supplier R&D Systems
Catalog 1071
Prices $75.00
Sizes 100 mg
Cas Number 29868-97-1
Chemical Name 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-onedihydrochloride
Formula C19H21N5O2.2HCl
Molecular Weight 424.33
Purity >98%
Supplier Page Shop

Product References

Presynaptic muscarinic acetylcholine autoreceptors (M1, M2 and M4 subtypes), - Presynaptic muscarinic acetylcholine autoreceptors (M1, M2 and M4 subtypes),

Nadal L, Garcia N, Hurtado E, Simo A, Tomas M, Lanuza MA, Santafe M, Tomas J. Mol Brain. 2016 Jun 23;9(1):67.

STEP activation by Galphaq coupled GPCRs opposes Src regulation of NMDA receptors - STEP activation by Galphaq coupled GPCRs opposes Src regulation of NMDA receptors

Tian M, Xu J, Lei G, Lombroso PJ, Jackson MF, MacDonald JF. Sci Rep. 2016 Nov 18;6:36684.

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial - Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial

Ahmed M, VanPatten S, Lakshminrusimha S, Patel H, Coleman TR, Al-Abed Y. Physiol Rep. 2016 Dec;4(24). pii: e13069.

Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by - Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by

Pediani JD, Ward RJ, Godin AG, Marsango S, Milligan G. J Biol Chem. 2016 Jun 17;291(25):13132-46.

Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term - Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term

Martin HG, Bernabeu A, Lassalle O, Bouille C, Beurrier C, Pelissier-Alicot AL, Manzoni OJ. Front Cell Neurosci. 2015 Dec 1;9:457.

Endogenous 17beta-estradiol is required for activity-dependent long-term - Endogenous 17beta-estradiol is required for activity-dependent long-term

Tozzi A, de Iure A, Tantucci M, Durante V, Quiroga-Varela A, Giampa C, Di Mauro M, Mazzocchetti P, Costa C, Di Filippo M, Grassi S, Pettorossi VE, Calabresi P. Front Cell Neurosci. 2015 May 27;9:192.

M2muscarinic receptors inhibit cell proliferation and migration in urothelial - M2muscarinic receptors inhibit cell proliferation and migration in urothelial

Pacini L, De Falco E, Di Bari M, Coccia A, Siciliano C, Ponti D, Pastore AL, Petrozza V, Carbone A, Tata AM, Calogero A. Cancer Biol Ther. 2014;15(11):1489-98.

An acetylcholinesterase inhibitor, eserine, induces long-term depression at - An acetylcholinesterase inhibitor, eserine, induces long-term depression at

Mans RA, Warmus BA, Smith CC, McMahon LL. J Neurophysiol. 2014 Nov 15;112(10):2388-97.

A2A adenosine receptor antagonism enhances synaptic and motor effects of cocaine - A2A adenosine receptor antagonism enhances synaptic and motor effects of cocaine

Tozzi A, de Iure A, Marsili V, Romano R, Tantucci M, Di Filippo M, Costa C, Napolitano F, Mercuri NB, Borsini F, Giampa C, Fusco FR, Picconi B, Usiello A, Calabresi P. PLoS One. 2012;7(6):e38312.

Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated - Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated

Buchanan KA, Petrovic MM, Chamberlain SE, Marrion NV, Mellor JR. Neuron. 2010 Dec 9;68(5):948-63.