EX 527

Name	EX 527
Supplier	R&D Systems
Catalog	2780
Prices	$89.00, $189.00, $765.00
Sizes	1 mg, 10 mg, 50 mg
Cas Number	49843-98-3
Chemical Name	6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Formula	C13H13ClN2O
Molecular Weight	248.71
Purity	>98%
Supplier Page	Shop

Product References

Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive - Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive

Weinberg RB, Mufson EJ, Counts SE. Front Neurosci. 2015 Nov 5;9:430.

SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1alpha (HIF-1alpha) - SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1alpha (HIF-1alpha)

Joo HY, Yun M, Jeong J, Park ER, Shin HJ, Woo SR, Jung JK, Kim YM, Park JJ, Kim J, Lee KH. Biochem Biophys Res Commun. 2015 Jul 10;462(4):294-300. doi:

SIRT1 deacetylates RORgammat and enhances Th17 cell generation. - SIRT1 deacetylates RORgammat and enhances Th17 cell generation.

Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnolzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E. J Exp Med. 2015 May 4;212(5):607-17.

Mir-34a mimics are potential therapeutic agents for p53-mutated and - Mir-34a mimics are potential therapeutic agents for p53-mutated and

Fan YN, Meley D, Pizer B, See V. PLoS One. 2014 Sep 24;9(9):e108514.

Regulation of neurons in the dorsal motor nucleus of the vagus by SIRT1. - Regulation of neurons in the dorsal motor nucleus of the vagus by SIRT1.

Jiang Y, Zsombok A. Front Neurosci. 2014 Jan 10;7:270.

Interferon regulatory factor 9 is critical for neointima formation following - Interferon regulatory factor 9 is critical for neointima formation following

Zhang SM, Zhu LH, Chen HZ, Zhang R, Zhang P, Jiang DS, Gao L, Tian S, Wang L, Zhang Y, Wang PX, Zhang XF, Zhang XD, Liu DP, Li H. Nat Commun. 2014 Oct 16;5:5160.

A critical role for interferon regulatory factor 9 in cerebral ischemic stroke. - A critical role for interferon regulatory factor 9 in cerebral ischemic stroke.

Chen HZ, Guo S, Li ZZ, Lu Y, Jiang DS, Zhang R, Lei H, Gao L, Zhang X, Zhang Y, Wang L, Zhu LH, Xiang M, Zhou Y, Wan Q, Dong H, Liu DP, Li H. J Neurosci. 2014 Sep 3;34(36):11897-912.

Defective expression of SIRT1 contributes to sustain inflammatory pathways in the - Defective expression of SIRT1 contributes to sustain inflammatory pathways in the

Caruso R, Marafini I, Franze E, Stolfi C, Zorzi F, Monteleone I, Caprioli F, Colantoni A, Sarra M, Sedda S, Biancone L, Sileri P, Sica GS, MacDonald TT, Pallone F, Monteleone G. Mucosal Immunol. 2014 Nov;7(6):1467-79.

Impaired cardiac SIRT1 activity by carbonyl stress contributes to aging-related - Impaired cardiac SIRT1 activity by carbonyl stress contributes to aging-related

Gu C, Xing Y, Jiang L, Chen M, Xu M, Yin Y, Li C, Yang Z, Yu L, Ma H. PLoS One. 2013 Sep 10;8(9):e74050.

SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in - SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in

Yan W, Fang Z, Yang Q, Dong H, Lu Y, Lei C, Xiong L. J Cereb Blood Flow Metab. 2013 Mar;33(3):396-406.