UNC 2400

• Supplier: R&D Systems
• Catalog: 4905
• Prices: $195.00
• Sizes: 10 mg
• Cas Number: 1433200-49-7
• Chemical Name: N-[(1,2-Dihydro-1,6-dimethyl-2-oxo-4-propyl-3-pyridinyl)methyl]-N-methyl-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide
• Formula: C35H47N7O2
• Molecular Weight: 597.79
• Purity: >98%

Product References

An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and - An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and

Konze KD, Ma A, Li F, Barsyte-Lovejoy D, Parton T, Macnevin CJ, Liu F, Gao C, Huang XP, Kuznetsova E, Rougie M, Jiang A, Pattenden SG, Norris JL, James LI, Roth BL, Brown PJ, Frye SV, Arrowsmith CH, Hahn KM, Wang GG, Vedadi M, Jin J. ACS Chem Biol. 2013;8(6):1324-34.

Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule - Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule

Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, Zheng D, Jin J, Wang GG. Blood. 2015 Jan 8;125(2):346-57.