XL 413 hydrochloride

• Supplier: R&D Systems
• Catalog: 5493
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1169562-71-3
• Chemical Name: 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-onehydrochloride
• Formula: C14H12ClN3O2.HCl
• Molecular Weight: 326.18
• Purity: >99%

Product References

The potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many - The potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many

Sasi NK, Tiwari K, Soon FF, Bonte D, Wang T, Melcher K, Xu HE, Weinreich M. PLoS One. 2014 Nov 20;9(11):e113300.

Discovery of XL413, a potent and selective CDC7 inhibitor. - Discovery of XL413, a potent and selective CDC7 inhibitor.

Koltun ES, Tsuhako AL, Brown DS, Aay N, Arcalas A, Chan V, Du H, Engst S, Ferguson K, Franzini M, Galan A, Holst CR, Huang P, Kane B, Kim MH, Li J, Markby D, Mohan M, Noson K, Plonowski A, Richards SJ, Robertson S, Shaw K, Stott G, Stout TJ, Young J, Yu P, Zaharia CA, Zhang W, Zhou P, Nuss JM, Xu W, Kearney PC. Bioorg Med Chem Lett. 2012 Jun 1;22(11):3727-31.