Ispinesib

• Supplier: R&D Systems
• Catalog: 5408
• Prices: $245.00, $1,005.00
• Sizes: 10 mg, 50 mg
• Cas Number: 336113-53-2
• Chemical Name: N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl]-4-methylbenzamide
• Formula: C30H33ClN4O2
• Molecular Weight: 517.06
• Purity: >98%

Product References

Mechanism of inhibition of human KSP by ispinesib. - Mechanism of inhibition of human KSP by ispinesib.

Lad L, Luo L, Carson JD, Wood KW, Hartman JJ, Copeland RA, Sakowicz R. Biochemistry. 2008 Mar 18;47(11):3576-85.

Increased therapeutic potential of an experimental anti-mitotic inhibitor - Increased therapeutic potential of an experimental anti-mitotic inhibitor

Davis DA, Sarkar SH, Hussain M, Li Y, Sarkar FH. BMC Cancer. 2006 Jan 24;6:22.

Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models - Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models

Purcell JW, Davis J, Reddy M, Martin S, Samayoa K, Vo H, Thomsen K, Bean P, Kuo WL, Ziyad S, Billig J, Feiler HS, Gray JW, Wood KW, Cases S. Clin Cancer Res. 2010 Jan 15;16(2):566-76.