SNS 314 mesylate

• Supplier: R&D Systems
• Catalog: 4584
• Prices: $225.00, $925.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1146618-41-8
• Chemical Name: N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]ureamethanesulfonate
• Formula: C18H15ClN6OS2.CH3SO3H
• Molecular Weight: 527.04
• Purity: >98%

Product References

SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and - SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and

Arbitrario JP, Belmont BJ, Evanchik MJ, Flanagan WM, Fucini RV, Hansen SK, Harris SO, Hashash A, Hoch U, Hogan JN, Howlett AR, Jacobs JW, Lam JW, Ritchie SC, Romanowski MJ, Silverman JA, Stockett DE, Teague JN, Zimmerman KM, Taverna P. Cancer Chemother Pharmacol. 2010 Mar;65(4):707-17. doi:

The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with - The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with

VanderPorten EC, Taverna P, Hogan JN, Ballinger MD, Flanagan WM, Fucini RV. Mol Cancer Ther. 2009 Apr;8(4):930-9.

Discovery of a potent and selective aurora kinase inhibitor. - Discovery of a potent and selective aurora kinase inhibitor.

Oslob JD, Romanowski MJ, Allen DA, Baskaran S, Bui M, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris S, Heumann SA, Hoch U, Jacobs JW, Lam J, Lawrence CE, McDowell RS, Nannini MA, Shen W, Silverman JA, Sopko MM, Tangonan BT, Teague J, Yoburn JC, Yu CH, Zhong M, Zimmerman KM, O'Brien T, Lew W. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4880-4.