TAK 960 hydrochloride

• Supplier: R&D Systems
• Catalog: 5403
• Prices: $255.00, $1,045.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1137868-96-2
• Chemical Name: 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamidehydrochloride
• Formula: C27H34F3N7O3.HCl
• Molecular Weight: 598.06
• Purity: >98%

Product References

TAK-960, a novel, orally available, selective inhibitor of polo-like kinase 1, - TAK-960, a novel, orally available, selective inhibitor of polo-like kinase 1,

Hikichi Y, Honda K, Hikami K, Miyashita H, Kaieda I, Murai S, Uchiyama N, Hasegawa M, Kawamoto T, Sato T, Ichikawa T, Cao S, Nie Z, Zhang L, Yang J, Kuida K, Kupperman E. Mol Cancer Ther. 2012 Mar;11(3):700-9.

Discovery of TAK-960: an orally available small molecule inhibitor of polo-like - Discovery of TAK-960: an orally available small molecule inhibitor of polo-like

Nie Z, Feher V, Natala S, McBride C, Kiryanov A, Jones B, Lam B, Liu Y, Kaldor S, Stafford J, Hikami K, Uchiyama N, Kawamoto T, Hikichi Y, Matsumoto S, Amano N, Zhang L, Hosfield D, Skene R, Zou H, Cao X, Ichikawa T. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3662-6.