BIX 02189

• Supplier: R&D Systems
• Catalog: 4842
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1265916-41-3
• Chemical Name: (3Z)-3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide
• Formula: C27H28N4O2
• Molecular Weight: 440.54
• Purity: >98%

Product References

Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. - Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.

Tatake RJ, O'Neill MM, Kennedy CA, Wayne AL, Jakes S, Wu D, Kugler SZ Jr, Kashem MA, Kaplita P, Snow RJ. Biochem Biophys Res Commun. 2008 Dec 5;377(1):120-5. doi:

Extracellular-signal-regulated kinase 5 modulates the antioxidant response by - Extracellular-signal-regulated kinase 5 modulates the antioxidant response by

Lopez-Royuela N, Rathore MG, Allende-Vega N, Annicotte JS, Fajas L, Ramachandran B, Gulick T, Villalba M. Int J Biochem Cell Biol. 2014 Aug;53:253-61.

Targeted deletion of the extracellular signal-regulated protein kinase 5 - Targeted deletion of the extracellular signal-regulated protein kinase 5

Kimura TE, Jin J, Zi M, Prehar S, Liu W, Oceandy D, Abe J, Neyses L, Weston AH, Cartwright EJ, Wang X. Circ Res. 2010 Mar 19;106(5):961-70.