PD 180970

Name PD 180970
Supplier R&D Systems
Catalog 4965
Prices $225.00
Sizes 10 mg
Cas Number 287204-45-9
Chemical Name 6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one
Formula C21H15Cl2FN4O
Molecular Weight 429.27
Purity >98%
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Product References

The pyrido[2,3-d]pyrimidine derivative PD180970 inhibits p210Bcr-Abl tyrosine - The pyrido[2,3-d]pyrimidine derivative PD180970 inhibits p210Bcr-Abl tyrosine

Dorsey JF, Jove R, Kraker AJ, Wu J. Cancer Res. 2000 Jun 15;60(12):3127-31.

Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and - Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and

Corbin AS, Griswold IJ, La Rosee P, Yee KW, Heinrich MC, Reimer CL, Druker BJ, Deininger MW. Blood. 2004 Dec 1;104(12):3754-7. Epub 2004 Aug 10.

Activity of the Bcr-Abl kinase inhibitor PD180970 against clinically relevant - Activity of the Bcr-Abl kinase inhibitor PD180970 against clinically relevant

La Rosee P, Corbin AS, Stoffregen EP, Deininger MW, Druker BJ. Cancer Res. 2002 Dec 15;62(24):7149-53.