(±)-AMG 487

• Supplier: R&D Systems
• Catalog: 4487
• Prices: $235.00, $965.00
• Sizes: 10 mg, 50 mg
• Cas Number: 947536-03-0
• Chemical Name: N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide
• Formula: C32H28F3N5O4
• Molecular Weight: 603.59
• Purity: >98%

Product References

Discovery and optimization of a series of quinazolinone-derived antagonists of - Discovery and optimization of a series of quinazolinone-derived antagonists of

Johnson M, Li AR, Liu J, Fu Z, Zhu L, Miao S, Wang X, Xu Q, Huang A, Marcus A, Xu F, Ebsworth K, Sablan E, Danao J, Kumer J, Dairaghi D, Lawrence C, Sullivan T, Tonn G, Schall T, Collins T, Medina J. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3339-43. Epub 2007 Apr 6.

Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic - Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic

Walser TC, Rifat S, Ma X, Kundu N, Ward C, Goloubeva O, Johnson MG, Medina JC, Collins TL, Fulton AM. Cancer Res. 2006 Aug 1;66(15):7701-7.

Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism. - Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism.

Cambien B, Karimdjee BF, Richard-Fiardo P, Bziouech H, Barthel R, Millet MA, Martini V, Birnbaum D, Scoazec JY, Abello J, Al Saati T, Johnson MG, Sullivan TJ, Medina JC, Collins TL, Schmid-Alliana A, Schmid-Antomarchi H. Br J Cancer. 2009 Jun 2;100(11):1755-64.