C16

Name C16
Supplier R&D Systems
Catalog 5382
Prices $129.00, $535.00
Sizes 10 mg, 50 mg
Cas Number 608512-97-6
Chemical Name 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one
Formula C13H8N4OS
Molecular Weight 268.29
Purity >98%
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Product References

Small molecule inhibitors of the RNA-dependent protein kinase. - Small molecule inhibitors of the RNA-dependent protein kinase.

Jammi NV, Whitby LR, Beal PA. Biochem Biophys Res Commun. 2003 Aug 15;308(1):50-7.

The oxindole/imidazole derivative C16 reduces in vivo brain PKR activation. - The oxindole/imidazole derivative C16 reduces in vivo brain PKR activation.

Ingrand S, Barrier L, Lafay-Chebassier C, Fauconneau B, Page G, Hugon J. FEBS Lett. 2007 Sep 18;581(23):4473-8. Epub 2007 Aug 21.

Prevention of the beta-amyloid peptide-induced inflammatory process by inhibition - Prevention of the beta-amyloid peptide-induced inflammatory process by inhibition

Couturier J, Paccalin M, Morel M, Terro F, Milin S, Pontcharraud R, Fauconneau B, Page G. J Neuroinflammation. 2011 Jun 23;8:72.

The specific PKR inhibitor C16 prevents apoptosis and IL-1beta production in an - The specific PKR inhibitor C16 prevents apoptosis and IL-1beta production in an

Tronel C, Page G, Bodard S, Chalon S, Antier D. Neurochem Int. 2014 Jan;64:73-83.