ERK5-IN-1

• Supplier: R&D Systems
• Catalog: 5393
• Prices: $245.00, $1,005.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1435488-37-1
• Chemical Name: 11-Cyclopentyl-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dihydro-5-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
• Formula: C36H46N8O3
• Molecular Weight: 638.8
• Purity: >98%

Product References

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 - Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2

Deng X, Elkins JM, Zhang J, Yang Q, Erazo T, Gomez N, Choi HG, Wang J, Dzamko N, Lee JD, Sim T, Kim N, Alessi DR, Lizcano JM, Knapp S, Gray NS. Eur J Med Chem. 2013;70:758-67.

X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor. - X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor.

Elkins JM, Wang J, Deng X, Pattison MJ, Arthur JS, Erazo T, Gomez N, Lizcano JM, Gray NS, Knapp S. J Med Chem. 2013 Jun 13;56(11):4413-21.