SCH 529074

• Supplier: R&D Systems
• Catalog: 4240
• Prices: $195.00, $805.00
• Sizes: 10 mg, 50 mg
• Cas Number: 922150-11-6
• Chemical Name: N3-[2-[[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]methyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine
• Formula: C31H36Cl2N6
• Molecular Weight: 563.56
• Purity: >98%

Product References

SCH529074, a small molecule activator of mutant p53, which binds p53 DNA binding - SCH529074, a small molecule activator of mutant p53, which binds p53 DNA binding

Demma M, Maxwell E, Ramos R, Liang L, Li C, Hesk D, Rossman R, Mallams A, Doll R, Liu M, Seidel-Dugan C, Bishop WR, Dasmahapatra B. J Biol Chem. 2010 Apr 2;285(14):10198-212.

Translational approaches targeting the p53 pathway for anti-cancer therapy. - Translational approaches targeting the p53 pathway for anti-cancer therapy.

Essmann F, Schulze-Osthoff K. Br J Pharmacol. 2012 Jan;165(2):328-44.