GNTI dihydrochloride

• Supplier: R&D Systems
• Catalog: 1282
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 351183-88-5
• Chemical Name: 5'-Guanidinyl-17-(cyclopropylmethyl)-6,7-dehydro-4,5α-epoxy-3,14-dihydroxy-6,7-2',3'-indolomorphinandihydrochloride
• Formula: C27H29N5O3.2HCl
• Molecular Weight: 544.48
• Purity: >96%

Product References

5'-Guanidinonaltrindole, a highly selective and potent kappa-opioid receptor - 5'-Guanidinonaltrindole, a highly selective and potent kappa-opioid receptor

Jones RM, Portoghese PS. Eur J Pharmacol. 2000 May 12;396(1):49-52.

The kappa-opioid antagonist GNTI reduces U50,488-, DAMGO-, and - The kappa-opioid antagonist GNTI reduces U50,488-, DAMGO-, and

Jewett DC, Grace MK, Jones RM, Billington CJ, Portoghese PS, Levine AS. Brain Res. 2001 Aug 3;909(1-2):75-80.

Mutational evidence for a common kappa antagonist binding pocket in the wild-type - Mutational evidence for a common kappa antagonist binding pocket in the wild-type

Jones RM, Hjorth SA, Schwartz TW, Portoghese PS. J Med Chem. 1998 Dec 3;41(25):4911-4.