GSK 650394

• Supplier: R&D Systems
• Catalog: 3572
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 890842-28-1
• Chemical Name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
• Formula: C25H22N2O2
• Molecular Weight: 382.45
• Purity: >97%

Product References

SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-alpha. - SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-alpha.

Pastore D, Della-Morte D, Coppola A, Capuani B, Lombardo MF, Pacifici F, Ferrelli F, Arriga R, Mammi C, Federici M, Bellia A, Di Daniele N, Tesauro M, Donadel G, Noto D, Sbraccia P, Sconocchia G, Lauro D. Cell Death Dis. 2015 Sep 17;6:e1890.

A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 - A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1

Beauchamp RL, James MF, DeSouza PA, Wagh V, Zhao WN, Jordan JT, Stemmer-Rachamimov A, Plotkin SR, Gusella JF, Haggarty SJ, Ramesh V. Oncotarget. 2015 Jul 10;6(19):16981-97.

Excess salt exacerbates blood-brain barrier disruption via a - Excess salt exacerbates blood-brain barrier disruption via a

Zhang T, Fang S, Wan C, Kong Q, Wang G, Wang S, Zhang H, Zou H, Sun B, Sun W, Zhang Y, Mu L, Wang J, Wang J, Zhang H, Wang D, Li H. Sci Rep. 2015 Nov 9;5:16548.

Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells. - Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells.

Hernandez AL, Kitz A, Wu C, Lowther DE, Rodriguez DM, Vudattu N, Deng S, Herold KC, Kuchroo VK, Kleinewietfeld M, Hafler DA. J Clin Invest. 2015 Nov 2;125(11):4212-22.

Rapid elevation of sodium transport through insulin is mediated by AKT in - Rapid elevation of sodium transport through insulin is mediated by AKT in

Mattes C, Laube M, Thome UH. Physiol Rep. 2014 Mar 20;2(3):e00269.

Serum- and glucocorticoid-induced protein kinase 1 (SGK1) increases the cystic - Serum- and glucocorticoid-induced protein kinase 1 (SGK1) increases the cystic

Koeppen K, Coutermarsh BA, Madden DR, Stanton BA. J Biol Chem. 2014 Jun 13;289(24):17142-50.

Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during - Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during

Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MK, Renshaw SA. J Immunol. 2014 Feb 15;192(4):1796-805.

Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: - Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids:

Kaiser G, Gerst F, Michael D, Berchtold S, Friedrich B, Strutz-Seebohm N, Lang F, Haring HU, Ullrich S. Diabetologia. 2013 Jul;56(7):1587-95.

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 - Sodium chloride drives autoimmune disease by the induction of pathogenic TH17

Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN, Hafler DA. Nature. 2013 Apr 25;496(7446):518-22.

Spinal serum-inducible and glucocorticoid-inducible kinase 1 mediates neuropathic - Spinal serum-inducible and glucocorticoid-inducible kinase 1 mediates neuropathic

Peng HY, Chen GD, Lai CY, Hsieh MC, Lin TB. J Neurosci. 2013 Mar 20;33(12):5227-40.