SB 269970 hydrochloride

• Supplier: R&D Systems
• Catalog: 1612
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 261901-57-9
• Chemical Name: (2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidinehydrochloride
• Formula: C18H28N2O3S.HCl
• Molecular Weight: 388.95
• Purity: >98%

Product References

Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 - Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42

Speranza L, Giuliano T, Volpicelli F, De Stefano ME, Lombardi L, Chambery A, Lacivita E, Leopoldo M, Bellenchi GC, di Porzio U, Crispino M, Perrone-Capano C. Front Behav Neurosci. 2015 Mar 11;9:62.

5-HT is a potent relaxant in rat superior mesenteric veins. - 5-HT is a potent relaxant in rat superior mesenteric veins.

Watts SW, Darios ES, Seitz BM, Thompson JM. Pharmacol Res Perspect. 2015 Feb;3(1):e00103.

5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect - 5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect

Chien CC, Su MJ. J Biomed Sci. 2015 Jun 16;22:42.

Effect of peripheral 5-HT on glucose and lipid metabolism in wether sheep. - Effect of peripheral 5-HT on glucose and lipid metabolism in wether sheep.

Watanabe H, Saito R, Nakano T, Takahashi H, Takahashi Y, Sumiyoshi K, Sato K, Chen X, Okada N, Iwasaki S, Harjanti DW, Sekiguchi N, Sano H, Kitazawa H, Rose MT, Ohwada S, Watanabe K, Aso H. PLoS One. 2014 Feb 4;9(2):e88058.

Dual effects of 5-HT(1a) receptor activation on breathing in neonatal mice. - Dual effects of 5-HT(1a) receptor activation on breathing in neonatal mice.

Corcoran AE, Commons KG, Wu Y, Smith JC, Harris MB, Richerson GB. J Neurosci. 2014 Jan 1;34(1):51-9.

Effects of the selective 5-HT7 receptor antagonist SB-269970 and amisulpride on - Effects of the selective 5-HT7 receptor antagonist SB-269970 and amisulpride on

Nikiforuk A, Kos T, Fijal K, Holuj M, Rafa D, Popik P. PLoS One. 2013 Jun 11;8(6):e66695.

Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates - Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates

Kim JJ, Bridle BW, Ghia JE, Wang H, Syed SN, Manocha MM, Rengasamy P, Shajib MS, Wan Y, Hedlund PB, Khan WI. J Immunol. 2013 May 1;190(9):4795-804.

Expression of serotonin receptors in human hepatocellular cancer. - Expression of serotonin receptors in human hepatocellular cancer.

Soll C, Riener MO, Oberkofler CE, Hellerbrand C, Wild PJ, DeOliveira ML, Clavien PA. Clin Cancer Res. 2012 Nov 1;18(21):5902-10.

Pharmacological blockade of serotonin 5-HT(7) receptor reverses working memory - Pharmacological blockade of serotonin 5-HT(7) receptor reverses working memory

Bonaventure P, Aluisio L, Shoblock J, Boggs JD, Fraser IC, Lord B, Lovenberg TW, Galici R. PLoS One. 2011;6(6):e20210.

5-hydroxytryptamine modulates migration, cytokine and chemokine release and - 5-hydroxytryptamine modulates migration, cytokine and chemokine release and

Muller T, Durk T, Blumenthal B, Grimm M, Cicko S, Panther E, Sorichter S, Herouy Y, Di Virgilio F, Ferrari D, Norgauer J, Idzko M. PLoS One. 2009 Jul 31;4(7):e6453.