HKI 357

• Supplier: R&D Systems
• Catalog: 3580
• Prices: $255.00, $1,045.00
• Sizes: 10 mg, 50 mg
• Cas Number: 848133-17-5
• Chemical Name: (2E)-N-[[4-[[(3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
• Formula: C31H29ClFN5O3
• Molecular Weight: 574.05
• Purity: >98%

Product References

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to - Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to

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Optimization of 6,7-disubstituted-4-(arylamino)quinoline-3-carbonitriles as - Optimization of 6,7-disubstituted-4-(arylamino)quinoline-3-carbonitriles as

Tsou HR, Overbeek-Klumpers EG, Hallett WA, Reich MF, Floyd MB, Johnson BD, Michalak RS, Nilakantan R, Discafani C, Golas J, Rabindran SK, Shen R, Shi X, Wang YF, Upeslacis J, Wissner A. J Med Chem. 2005 Feb 24;48(4):1107-31.

Pharmacology and signaling properties of epidermal growth factor receptor - Pharmacology and signaling properties of epidermal growth factor receptor

Schiffer HH, Reding EC, Fuhs SR, Lu Q, Piu F, Wong S, Littler PL, Weiner DM, Keefe W, Tan PK, Nash NR, Knapp AE, Olsson R, Brann MR. Mol Pharmacol. 2007 Feb;71(2):508-18. Epub 2006 Sep 12.