A 943931 dihydrochloride

• Supplier: R&D Systems
• Catalog: 3753
• Prices: $205.00, $845.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1227675-50-4
• Chemical Name: 4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine
• Formula: C17H21N5.2HCl
• Molecular Weight: 368.31
• Purity: >98%

Product References

Histamine H4-receptors inhibit mast cell renin release in ischemia/reperfusion - Histamine H4-receptors inhibit mast cell renin release in ischemia/reperfusion

Aldi S, Takano K, Tomita K, Koda K, Chan NY, Marino A, Salazar-Rodriguez M, Thurmond RL, Levi R. J Pharmacol Exp Ther. 2014 Jun;349(3):508-17.

Molecular and biochemical pharmacology of the histamine H4 receptor. - Molecular and biochemical pharmacology of the histamine H4 receptor.

Leurs R, Chazot PL, Shenton FC, Lim HD, de Esch IJ. Br J Pharmacol. 2009 May;157(1):14-23.

Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class - Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class

Cowart MD, Altenbach RJ, Liu H, Hsieh GC, Drizin I, Milicic I, Miller TR, Witte DG, Wishart N, Fix-Stenzel SR, McPherson MJ, Adair RM, Wetter JM, Bettencourt BM, Marsh KC, Sullivan JP, Honore P, Esbenshade TA, Brioni JD. J Med Chem. 2008 Oct 23;51(20):6547-57.