UK 78282 hydrochloride

• Supplier: R&D Systems
• Catalog: 3829
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 136647-02-4
• Chemical Name: 4-[(Diphenylmethoxy)methyl]-1-[3-(4-methoxyphenyl)propyl]-piperidinehydrochloride
• Formula: C29H35NO2.HCl
• Molecular Weight: 466.05
• Purity: >99%

Product References

UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 - UK-78,282, a novel piperidine compound that potently blocks the Kv1.3

Hanson DC, Nguyen A, Mather RJ, Rauer H, Koch K, Burgess LE, Rizzi JP, Donovan CB, Bruns MJ, Canniff PC, Cunningham AC, Verdries KA, Mena E, Kath JC, Gutman GA, Cahalan MD, Grissmer S, Chandy KG. Br J Pharmacol. 1999 Apr;126(8):1707-16.

Potassium channels in T lymphocytes: toxins to therapeutic immunosuppressants. - Potassium channels in T lymphocytes: toxins to therapeutic immunosuppressants.

Chandy KG, Cahalan M, Pennington M, Norton RS, Wulff H, Gutman GA. Toxicon. 2001 Sep;39(9):1269-76.

K+ channels as targets for specific immunomodulation. - K+ channels as targets for specific immunomodulation.

Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. Trends Pharmacol Sci. 2004 May;25(5):280-9.