SGI 1027

• Supplier: R&D Systems
• Catalog: 5155
• Prices: $179.00, $745.00
• Sizes: 10 mg, 50 mg
• Cas Number: 1020149-73-8
• Chemical Name: N-[4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide
• Formula: C27H23N7O
• Molecular Weight: 461.52
• Purity: >99%

Product References

A new class of quinoline-based DNA hypomethylating agents reactivates tumor - A new class of quinoline-based DNA hypomethylating agents reactivates tumor

Datta J, Ghoshal K, Denny WA, Gamage SA, Brooke DG, Phiasivongsa P, Redkar S, Jacob ST. Cancer Res. 2009 May 15;69(10):4277-85.

Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia - Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia

Garcia-Dominguez P, Dell'aversana C, Alvarez R, Altucci L, de Lera AR. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1631-5.