ZM 447439

• Supplier: R&D Systems
• Catalog: 2458
• Prices: $245.00
• Sizes: 10 mg
• Cas Number: 331771-20-1
• Chemical Name: N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
• Formula: C29H31N5O4
• Molecular Weight: 513.59
• Purity: >98%

Product References

Stable kinetochore-microtubule attachment is sufficient to silence the spindle - Stable kinetochore-microtubule attachment is sufficient to silence the spindle

Tauchman EC, Boehm FJ, DeLuca JG. Nat Commun. 2015 Dec 1;6:10036.

Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic - Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic

Platani M, Trinkle-Mulcahy L, Porter M, Jeyaprakash AA, Earnshaw WC. J Cell Biol. 2015 Jul 6;210(1):45-62.

Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human - Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human

Kim S, Yu H. J Cell Biol. 2015 Jan 19;208(2):181-96.

Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular - Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular

Maki-Jouppila JH, Laine LJ, Rehnberg J, Narvi E, Tiikkainen P, Hukasova E, Halonen P, Lindqvist A, Kallio L, Poso A, Kallio MJ. Mol Cancer Ther. 2014 May;13(5):1054-66.

Selective disruption of aurora C kinase reveals distinct functions from aurora B - Selective disruption of aurora C kinase reveals distinct functions from aurora B

Balboula AZ, Schindler K. PLoS Genet. 2014 Feb 27;10(2):e1004194.

Aurora B spatially regulates EB3 phosphorylation to coordinate daughter cell - Aurora B spatially regulates EB3 phosphorylation to coordinate daughter cell

Ferreira JG, Pereira AJ, Akhmanova A, Maiato H. J Cell Biol. 2013 May 27;201(5):709-24.

Spatiotemporal organization of Aurora-B by APC/CCdh1 after mitosis coordinates - Spatiotemporal organization of Aurora-B by APC/CCdh1 after mitosis coordinates

Floyd S, Whiffin N, Gavilan MP, Kutscheidt S, De Luca M, Marcozzi C, Min M, Watkins J, Chung K, Fackler OT, Lindon C. J Cell Sci. 2013 Jul 1;126(Pt 13):2845-56.

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome - Haspin inhibitors reveal centromeric functions of Aurora B in chromosome

Wang F, Ulyanova NP, Daum JR, Patnaik D, Kateneva AV, Gorbsky GJ, Higgins JM. J Cell Biol. 2012 Oct 15;199(2):251-68.

Aurora kinase B activity is modulated by thyroid hormone during transcriptional - Aurora kinase B activity is modulated by thyroid hormone during transcriptional

Tardaguila M, Gonzalez-Gugel E, Sanchez-Pacheco A. Mol Endocrinol. 2011 Mar;25(3):385-93.

Zwint-1 is a novel Aurora B substrate required for the assembly of a - Zwint-1 is a novel Aurora B substrate required for the assembly of a

Kasuboski JM, Bader JR, Vaughan PS, Tauhata SB, Winding M, Morrissey MA, Joyce MV, Boggess W, Vos L, Chan GK, Hinchcliffe EH, Vaughan KT. Mol Biol Cell. 2011 Sep;22(18):3318-30.