GANT 58

• Supplier: R&D Systems
• Catalog: 3889
• Prices: $159.00, $665.00
• Sizes: 10 mg, 50 mg
• Cas Number: 64048-12-0
• Chemical Name: 2,3,4,5-Tetra(4-pyridyl)thiophene
• Formula: C24H16N4S
• Molecular Weight: 392.48
• Purity: >99%

Product References

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule - Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule

Lauth M, Bergstrom A, Shimokawa T, Toftgard R. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8455-60. Epub 2007 May 9.

GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein. - GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.

Beauchamp E, Bulut G, Abaan O, Chen K, Merchant A, Matsui W, Endo Y, Rubin JS, Toretsky J, Uren A. J Biol Chem. 2009 Apr 3;284(14):9074-82.

GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors. - GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.

Joo J, Christensen L, Warner K, States L, Kang HG, Vo K, Lawlor ER, May WA. PLoS One. 2009 Oct 27;4(10):e7608.