BAY 41-2272

• Supplier: R&D Systems
• Catalog: 4430
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 256376-24-6
• Chemical Name: 5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
• Formula: C20H17FN6
• Molecular Weight: 360.39
• Purity: >98%

Product References

NO-independent regulatory site on soluble guanylate cyclase. - NO-independent regulatory site on soluble guanylate cyclase.

Stasch JP, Becker EM, Alonso-Alija C, Apeler H, Dembowsky K, Feurer A, Gerzer R, Minuth T, Perzborn E, Pleiss U, Schroder H, Schroeder W, Stahl E, Steinke W, Straub A, Schramm M. Nature. 2001 Mar 8;410(6825):212-5.

The soluble guanylate cyclase stimulator BAY 41-2272 inhibits vascular smooth - The soluble guanylate cyclase stimulator BAY 41-2272 inhibits vascular smooth

Joshi CN, Martin DN, Fox JC, Mendelev NN, Brown TA, Tulis DA. J Pharmacol Exp Ther. 2011 Nov;339(2):394-402.

Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble - Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble

Mittendorf J, Weigand S, Alonso-Alija C, Bischoff E, Feurer A, Gerisch M, Kern A, Knorr A, Lang D, Muenter K, Radtke M, Schirok H, Schlemmer KH, Stahl E, Straub A, Wunder F, Stasch JP. ChemMedChem. 2009 May;4(5):853-65.