GW 843682X

• Supplier: R&D Systems
• Catalog: 2977
• Prices: $95.00, $199.00, $825.00
• Sizes: 1 mg, 10 mg, 50 mg
• Cas Number: 660868-91-7
• Chemical Name: 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide
• Formula: C22H18F3N3O4S
• Molecular Weight: 477.46
• Purity: >98%

Product References

Requirement for PLK1 kinase activity in the maintenance of a robust spindle - Requirement for PLK1 kinase activity in the maintenance of a robust spindle

O'Connor A, Maffini S, Rainey MD, Kaczmarczyk A, Gaboriau D, Musacchio A, Santocanale C. Biol Open. 2015 Dec 18;5(1):11-9.

The Centriole Cartwheel Protein SAS-6 in Trypanosoma brucei Is Required for - The Centriole Cartwheel Protein SAS-6 in Trypanosoma brucei Is Required for

Hu H, Liu Y, Zhou Q, Siegel S, Li Z. Eukaryot Cell. 2015 Sep;14(9):898-907.

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. - Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.

Barton O, Naumann SC, Diemer-Biehs R, Kunzel J, Steinlage M, Conrad S, Makharashvili N, Wang J, Feng L, Lopez BS, Paull TT, Chen J, Jeggo PA, Lobrich M. J Cell Biol. 2014 Sep 29;206(7):877-94.

Polo-like kinase 1 (PLK1) is involved in toll-like receptor (TLR)-mediated - Polo-like kinase 1 (PLK1) is involved in toll-like receptor (TLR)-mediated

Hu J, Wang G, Liu X, Zhou L, Jiang M, Yang L. PLoS One. 2013 Oct 18;8(10):e78832.

Role of a novel coiled-coil domain-containing protein CCDC69 in regulating - Role of a novel coiled-coil domain-containing protein CCDC69 in regulating

Pal D, Wu D, Haruta A, Matsumura F, Wei Q. Cell Cycle. 2010 Oct 15;9(20):4117-29. Epub 2010 Oct 22.

Liaisons between survivin and Plk1 during cell division and cell death. - Liaisons between survivin and Plk1 during cell division and cell death.

Colnaghi R, Wheatley SP. J Biol Chem. 2010 Jul 16;285(29):22592-604.

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, - Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1,

Manchado E, Guillamot M, de Carcer G, Eguren M, Trickey M, Garcia-Higuera I, Moreno S, Yamano H, Canamero M, Malumbres M. Cancer Cell. 2010 Dec 14;18(6):641-54.

Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants - Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants

Scutt PJ, Chu ML, Sloane DA, Cherry M, Bignell CR, Williams DH, Eyers PA. J Biol Chem. 2009 Jun 5;284(23):15880-93.