Macbecin I

• Supplier: R&D Systems
• Catalog: 3061
• Prices: $269.00
• Sizes: 1 mg
• Cas Number: 73341-72-7
• Chemical Name: (15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin
• Formula: C30H42N2O8
• Molecular Weight: 558.67

Product References

Antitumor and cytocidal activities of a newly isolated benzenoid ansamycin, - Antitumor and cytocidal activities of a newly isolated benzenoid ansamycin,

Ono Y, Kozai Y, Ootsu K. Gan. 1982 Dec;73(6):938-44.

Natural product origins of Hsp90 inhibitors. - Natural product origins of Hsp90 inhibitors.

Uehara Y. Curr Cancer Drug Targets. 2003 Oct;3(5):325-30.

Molecular characterization of macbecin as an Hsp90 inhibitor. - Molecular characterization of macbecin as an Hsp90 inhibitor.

Martin CJ, Gaisser S, Challis IR, Carletti I, Wilkinson B, Gregory M, Prodromou C, Roe SM, Pearl LH, Boyd SM, Zhang MQ. J Med Chem. 2008 May 8;51(9):2853-7.