AR-C 102222

• Supplier: R&D Systems
• Catalog: 3969
• Prices: $225.00, $925.00
• Sizes: 10 mg, 50 mg
• Cas Number: 253771-21-0
• Chemical Name: 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrilehydrochloride
• Formula: C19H16F2N6O.HCl
• Molecular Weight: 418.83
• Purity: >98%

Product References

1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible - 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible

Tinker AC, Beaton HG, Boughton-Smith N, Cook TR, Cooper SL, Fraser-Rae L, Hallam K, Hamley P, McInally T, Nicholls DJ, Pimm AD, Wallace AV. J Med Chem. 2003 Mar 13;46(6):913-6.

Antinociceptive activity of the selective iNOS inhibitor AR-C102222 in rodent - Antinociceptive activity of the selective iNOS inhibitor AR-C102222 in rodent

LaBuda CJ, Koblish M, Tuthill P, Dolle RE, Little PJ. Eur J Pain. 2006 Aug;10(6):505-12. Epub 2005 Aug 24.

Discovery of inducible nitric oxide synthase (iNOS) inhibitor development - Discovery of inducible nitric oxide synthase (iNOS) inhibitor development

Bonnefous C, Payne JE, Roppe J, Zhuang H, Chen X, Symons KT, Nguyen PM, Sablad M, Rozenkrants N, Zhang Y, Wang L, Severance D, Walsh JP, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND. J Med Chem. 2009 May 14;52(9):3047-62.