PD 173074

• Supplier: R&D Systems
• Catalog: 3044
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Cas Number: 219580-11-7
• Chemical Name: N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
• Formula: C28H41N7O3
• Molecular Weight: 523.67
• Purity: >98%

Product References

A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation - A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation

Benzina S, Pitaval A, Lemercier C, Lustremant C, Frouin V, Wu N, Papine A, Soussaline F, Romeo PH, Gidrol X. Cell Mol Life Sci. 2015 Sep;72(18):3559-73.

Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer - Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer

Knuchel S, Anderle P, Werfelli P, Diamantis E, Ruegg C. Oncotarget. 2015 Jun 10;6(16):14300-17.

A Molecular atlas of Xenopus respiratory system development. - A Molecular atlas of Xenopus respiratory system development.

Rankin SA, Thi Tran H, Wlizla M, Mancini P, Shifley ET, Bloor SD, Han L, Vleminckx K, Wert SE, Zorn AM. Dev Dyn. 2015 Jan;244(1):69-85.

Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem - Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem

Yang J, Kaur K, Ong LL, Eisenberg CA, Eisenberg LM. Stem Cells Int. 2015;2015:270428.

Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis. - Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis.

MacKenzie B, Korfei M, Henneke I, Sibinska Z, Tian X, Hezel S, Dilai S, Wasnick R, Schneider B, Wilhelm J, El Agha E, Klepetko W, Seeger W, Schermuly R, Gunther A, Bellusci S. Respir Res. 2015 Jul 3;16:83.

The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and - The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and

Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor AK, Yasuda Y, Niki T. BMC Cancer. 2015 Feb 25;15:82.

PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR. - PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR.

Anreddy N, Patel A, Sodani K, Kathawala RJ, Chen EP, Wurpel JN, Chen ZS. Acta Pharm Sin B. 2014 Jun;4(3):202-7.

Generation of the epicardial lineage from human pluripotent stem cells. - Generation of the epicardial lineage from human pluripotent stem cells.

Witty AD, Mihic A, Tam RY, Fisher SA, Mikryukov A, Shoichet MS, Li RK, Kattman SJ, Keller G. Nat Biotechnol. 2014 Oct;32(10):1026-35.

Modulation of pluripotency in the porcine embryo and iPS cells. - Modulation of pluripotency in the porcine embryo and iPS cells.

Rodriguez A, Allegrucci C, Alberio R. PLoS One. 2012;7(11):e49079.

Activation of glial FGFRs is essential in glial migration, proliferation, and - Activation of glial FGFRs is essential in glial migration, proliferation, and

Gibson NJ, Tolbert LP, Oland LA. PLoS One. 2012;7(4):e33828.