Crizotinib

• Supplier: R&D Systems
• Catalog: 4368
• Prices: $245.00, $1,005.00
• Sizes: 10 mg, 50 mg
• Cas Number: 877399-52-5
• Chemical Name: 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
• Formula: C21H22Cl2FN5O
• Molecular Weight: 450.34
• Purity: >99%

Product References

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53. - ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.

Sullivan KD, Padilla-Just N, Henry RE, Porter CC, Kim J, Tentler JJ, Eckhardt SG, Tan AC, DeGregori J, Espinosa JM. Nat Chem Biol. 2012 Jul;8(7):646-54.

Multiple mutations and bypass mechanisms can contribute to development of - Multiple mutations and bypass mechanisms can contribute to development of

Qi J, McTigue MA, Rogers A, Lifshits E, Christensen JG, Janne PA, Engelman JA. Cancer Res. 2011 Feb 1;71(3):1081-91.