A 1120

Name	A 1120
Supplier	Tocris Bioscience
Catalog	4431
Prices	$169.00, $705.00
Sizes	10 mg, 50 mg
Cas Number	1152782-19-8
Chemical Name	2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoicacid
Formula	C20H19F3N2O3
Molecular Weight	392.37
Purity	>99 %
Description	High affinity retinol-binding protein 4 (RBP4) ligand (K i = 8.3 nM); non-retinoid. Selective against a range of different cellular targets. As efficacious as fenretinide (Cat. No. 1396) in the reduction of serum RBP4 and retinol. Displaces transthyretin (TTR) from RBP4-TTR complexes.
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Product References

All-trans retinoic acid lowers serum retinol-binding protein 4 concentrations and - All-trans retinoic acid lowers serum retinol-binding protein 4 concentrations and

Manolescu DC, Sima A, Bhat PV. J Nutr. 2010 Feb;140(2):311-6.

Identification and characterization of a non-retinoid ligand for retinol-binding - Identification and characterization of a non-retinoid ligand for retinol-binding

Motani A, Wang Z, Conn M, Siegler K, Zhang Y, Liu Q, Johnstone S, Xu H, Thibault S, Wang Y, Fan P, Connors R, Le H, Xu G, Walker N, Shan B, Coward P. J Biol Chem. 2009 Mar 20;284(12):7673-80.