A 77636 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 3336
• Prices: $199.00, $825.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 145307-34-2
• Chemical Name: (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diolhydrochloride
• Formula: C20H27NO3.HCl
• Molecular Weight: 365.9
• Purity: >98 %
• Description: Potent and selective dopamine D 1 -like receptor agonist (pEC 50 values are 8.97 and < 5 for D 1 -like and D 2 -like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo .

Product References

A-77636: a potent and selective dopamine D1 receptor agonist with - A-77636: a potent and selective dopamine D1 receptor agonist with

Kebabian JW, Britton DR, DeNinno MP, Perner R, Smith L, Jenner P, Schoenleber R, Williams M. Eur J Pharmacol. 1992 Dec 15;229(2-3):203-9.

The potent and selective dopamine D1 receptor agonist A-77636 increases cortical - The potent and selective dopamine D1 receptor agonist A-77636 increases cortical

Acquas E, Day JC, Fibiger HC. Eur J Pharmacol. 1994 Jul 21;260(1):85-7.

Homologous desensitization of the D1A dopamine receptor: efficacy in causing - Homologous desensitization of the D1A dopamine receptor: efficacy in causing

Lewis MM, Watts VJ, Lawler CP, Nichols DE, Mailman RB. J Pharmacol Exp Ther. 1998 Jul;286(1):345-53.